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UC San Diego Nobel Laureate Roger Tsien Dies at 64

Xconomy

Roger Tsien, a UC San Diego scientist who shared the 2008 Nobel Prize in chemistry for research that led to the development of fluorescent proteins used to illuminate tissue and track biological processes, has died, according to a statement from the university.

EY Names 6 Startup Leaders as San Diego Entrepreneurs of the Year

Xconomy

Six San Diego business risk-takers have been inducted into the pantheon of EY Entrepreneurs of the Year, joining over 10,000 people around the world who have been honored over the last 30 years by the multinational professional services firm.

San Diego’s KnuEdge, Stealthy Since 2005, Unveils Neural Tech

Xconomy

After operating in the shadows for the past 11 years, a San Diego neural technology company founded by former NASA administrator Dan Goldin is stepping into the light to introduce two commercial products intended to advance the frontier of human-machine interaction.

Phoenix Shops Its Cancer Drug as Potential Alzheimer’s Treatment

Xconomy

San Antonio — George Perry, a scientist at the University of Texas at San Antonio, has long proposed that drug developers and researchers need to look earlier into the roots of Alzheimer’s disease.

Ex-Xerox CTO Vandebroek Named Chief Operating Officer of IBM Research

Xconomy

When I last spoke to Sophie Vandebroek in December, it was for a kind of exit interview as she prepared to leave her longtime job as Xerox’s CTO and head of its worldwide research organization. We went over highlights of her Xerox tenure, her outlook on key technology trends for 2017 and beyond—the Internet of Everything, cognitive computing, healthcare IT, and cybersecurity chief among them—and her own plans for the future. Re that last point—she seemed completely unsure.

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Synthetic Genomics Creates Host Organism Optimized for Bio Industry

Xconomy

Scientists from Synthetic Genomics, the San Diego-based industrial biotech, have re-engineered a fast-growing microorganism found in salt marsh mud to maximize its production of proteins and to optimize other common bio-based processes.

Xconomy Q&A: Vuforia, Pokémon Go, and Augmented Reality

Xconomy

It’s been less than a year since Needham, MA-based PTC (NASDAQ: PTC ) shelled out $65 million to acquire Vuforia, the augmented reality technology created by San Diego-based Qualcomm (NASDAQ: QCOM ). Talk about auspicious timing.

San Diego Sees Strong Cybersecurity Growth As Firms Seek Talent

Xconomy

San Diego’s cybersecurity workforce has grown by nearly 15 percent over the past two years, according to a study released today by the Cyber Center of Excellence, a nonprofit industry group created to boost cybersecurity jobs and technologies in the region. The center commissioned the report to help quantify the economic impact of the cybersecurity industry in San Diego, and to assess how employers view their prospects for growth and needs for future hiring.

Organovo to Test Pre-Clinical Drugs on Bio-Printed Kidney Tissue

Xconomy

Since then, the San Diego company has built a thriving business as a contract research organization (CRO) that tests experimental drug compounds on bio-printed liver tissue.

Qualcomm and AT&T Partner to Use Wireless Network for Drone Flights

Xconomy

After signaling that it plans to operate drones via cellular technologies, San Diego-based Qualcomm says today it is working with AT&T to use commercial wireless networks for test flights beyond an operator’s visual line of sight.

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Avalon Leads $18M in Early Funding for Cancer Immunotherapy Startup

Xconomy

Fortis Therapeutics, a new San Diego biotech, has raised $18 million in initial funding to develop drugs for hard-to-treat prostate and bone marrow cancers. Fortis also has recruited a prominent prostate cancer researcher, Eric Small of UCSF, to the company’s scientific advisory board.

Qualcomm Making Inroads with Wireless EV Charging Technology

Xconomy

The San Diego company sees many reasons why wireless charging will eventually become a robust global market, according to Steve Pazol, a Qualcomm vice president who took over the company’s wireless charging business in 2014.

ViaCyte Working with Gore to Improve its Synthetic Pancreas Device

Xconomy

San Diego-based ViaCyte said today it is collaborating with W.L. Gore & Associates, the privately held company that makes Gore-Tex fabrics, medical devices, and other products, in a bid to improve its stem cell-derived treatment for diabetes.

Want to Communicate Your Science? First, Step Back

Xconomy

Think for a moment about the words and phrases that life science researchers and executives use on a daily basis. I’m talking about the seemingly simple phrases like “investigational drug,” “novel target,” “immunotherapy,” “clinical trial,” “in vitro,” and “therapeutic window.”

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Protecting America’s Tech Prowess Amid the Hostile Rhetoric of 2017

Xconomy

Along with that comes the responsibility of leadership in developing the consensus to make long term investments in research and education and manage them effectively. With the inauguration of Donald Trump as president on January 20th, the editors asked some of our Xconomists to offer their thoughts on “How could the incoming administration significantly affect your industry?”

14 for ’17: Key Clinical Data To Watch For Next Year (Part 2)

Xconomy

Fox Foundation for Parkinson's Research Migraine ModeRNA Therapeutics Multiple Sclerosis National Institutes of Health National Multiple Sclerosis Society nicotine patch Novartis ocrelizmab ozanimod patisiran Pfizer phase 2 Phase 3 postpartum depression Receptos Repurpose RNA Interference RNAi Roche Sage Therapeutics SAGE-547 Sanofi Pasteur Servier Takeda Pharmaceutical Teva Tim Coetzee transthyretin amyloidosis UCART19 Vaccine Zika virus

BlackThorn Emerges With $40M, New Weapons Against Neuro Disorders

Xconomy

As Xconomy reported last year, South San Francisco, CA-based BlackThorn was spun out of Scripps Research Institute , which on its website lists the company as one of its 2013 spinouts. It’s emerging from clinical research.”.

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Precision Medicine In Trump Era? California Presses Own Modest Program

Xconomy

Bush healthcare Institute of Computational Health Sciences Life Sciences Obama PMI Precision Medicine Stem Cell Research UCSF University of California

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Machine Learning 201: Exploring the Market for New Business

Xconomy

2016 will be remembered for many things, not least as the year that AI and machine learning stepped into the technological and cultural spotlight. Advances in applied machine learning fueled our enthusiasm for smarter, more talkative devices.

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All In One Place: A New Immuno-Oncology Trial Resource

Xconomy

“Despite high rates of … remission, relapse is a significant [cause] of treatment failure,” wrote Rebecca Gardner of Seattle Children’s Research Institute and her colleagues this year in describing the results of one of their CAR-T studies.

Cybersecurity Startup MedCrypt Gets $750K to Defend Health Devices

Xconomy

MedCrypt, a healthtech cybersecurity startup founded near San Diego, has raised $750,000 in a seed financing round led by Safeguard Scientifics (NYSE: SFE ), a private equity fund in suburban Philadelphia that invests in healthcare, fintech, and digital media.

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Sluggish Year for IPOs, But Signs Abound of Post-Election Surge

Xconomy

The institutional research firm is predicting a surge of IPOs in the weeks and months to come. Uncertainty surrounding this year’s presidential election has kept U.S.

Toyota And Others Enabling Self-Driving Cars to Talk to Each Other

Xconomy

Drivers have plenty of ways to communicate with their fellow drivers, beyond the basic turn signal. Some methods are nice, like a friendly wave to beckon a merging car into your lane. Others, not so much. We’ve all probably cursed or honked at another driver, or been given the finger.

AACR Review: Biden Fired Up, Incyte Doubles Up, BMS Up And Down

Xconomy

The American Association for Cancer Research held its annual meeting this week in Washington, DC, a convenient venue for former Vice President Joe Biden to deliver a broadside against the Trump administration’s proposed budget cuts in science funding.

At Big Hemophilia Meeting, More Data, and Promise, For Gene Therapy

Xconomy

Merck Invests $90M In San Diego Research Group

socalTECH

Biopharmaceuticals giant Merck said today that it is investing $90M in setting up a new, San Diego research organization, called Calibr. According to Merck, the new, independent not-for-profit will aim to accelerate translation of basic biomedical research into new medicines to treat disease, and will be led by Peter G. z is a professor at The Scripps Research Institute. merck diego calibre research biotech lifescience small molecule biomedicine

Ex-Celgene Dealmaker Tom Daniel Charts a New Course Advising Biotechs

Xconomy

Xconomy has learned that Daniel stepped down from his role as president of research & early development at Celgene (NASDAQ: CELG ) over the summer, a position that has since been filled by Rupert Vessey.

Water Metering Startup Wins Vote for “Best Demo” at EvoNexus Event

Xconomy

A San Diego civil engineer who has developed an alternative technology for automating the measurement of water flow gave the best presentation at EvoNexus Fall Demo Day, an event that drew nearly 400 entrepreneurs, investors, and supporters late Thursday to Qualcomm’s corporate headquarters. EvoNexus operates as a free incubator (with “no strings attached”) for tech startups at three facilities in San Diego and Orange County.

Craig Venter Used Own Posh Health Clinic To Diagnose His Cancer

Xconomy

Speaking at a conference in San Francisco Wednesday, geneticist Craig Venter revealed that he had just had surgery for prostate cancer three weeks ago.

Wireless Technology Firm Opens San Diego Research Center

socalTECH

Pennsylvania-based InterDigital , a developer of wireless technology products, said Monday that it is opening up a new office in San Diego. According to the firm, the new West Coast Research and Development Center will help the firm tap into the region's ecosystem of innovation. diego expansion jobs employment wireless research interdigital

Watching for NIH Innovation in 2017—and Drug Pricing, Trade Deals

Xconomy

With the inauguration of Donald Trump as president on January 20th, the editors asked some of our Xconomists to offer their thoughts on “How could the incoming administration significantly affect your industry?” When I worked in the Reagan Administration, the “Gipper” used to handle questions like this by saying he couldn’t respond to hypothetical questions. That being said, here’s what I’ll be keeping an eye on in Washington in 2017.

Drug-Hunting Startup From Scripps Attracts Celgene Alum, $50M Backing

Xconomy

A team of decorated academic chemists in San Diego have been working since 2014 on a biotech startup that aims to find new drugs faster. The company now has a lot of cash in the bank and a well-known biopharma scientist to guide it.

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With New Program, DARPA To Encourage Safety “Brakes” For Gene Editing

Xconomy

Defense Advanced Research Projects Agency—a famed military R&D group—wants to finance safety measures for the new gene-editing age. “We should couple innovation with biosecurity,” DARPA program manager Renee Wegrzyn, said Tuesday at the SynBioBeta conference in South San Francisco. ” Some academic researchers and biotech firms are building safety nets into other cutting-edge therapies.

The Xconomy Immuno-Oncology Resource: A Mid-ASH T Cell Update

Xconomy

The past week brought a wave of clinical data from experimental programs that turn living T cells into revved-up cancer fighters, often extracted from a patient then re-introduced after being genetically engineered outside the patient’s body.

Inspired by NFL Teammate, Aethlon Seeks Diagnostic for Brain Injuries

Xconomy

Just as the NFL marketing machine is stoking the build-up to Super Bowl LI, a San Diego diagnostic company headed by a former Denver Broncos player has unveiled plans for a new clinical study of traumatic brain injuries among retired NFL players.

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New Data Show Biogen, Ionis Drug Might Help More With Rare Spine Disease

Xconomy

Evercore ISI analyst John Scotti wrote in a research note this morning that an estimated 2,500 patients in the U.S., It also helped fund the nusinersen program in 2003 when it started out as research at the University of Massachusetts, before it was licensed to Ionis.).

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Zavante Plans FDA Filing After Antibiotic Hits Clinical Trial Goals

Xconomy

Zavante Therapeutics has been researching one drug as a possible alternative and, with results from a key clinical trial now in hand, the company is preparing to file for FDA approval early next year.

Biogen Buys Ionis Spine Disease Drug For $75M, Eyes FDA Filing

Xconomy

Today is a hopeful day for the SMA community, which has worked tirelessly to support research and development for this terrible disease,” said Kenneth Hobby, the president of non-profit patient advocacy group Cure SMA, in a statement. “We

Study 30

Duchenne Lessons: Advocates For Rare Spinal Disease Have Eyes on FDA

Xconomy

Cure SMA backed early research that helped scientists understand the underlying cause of SMA. Patient groups help raise money for basic research and, if a drug emerges that seems promising, help recruit patients for trials.

Riding Moonshot, FDA Will Revamp Its Cancer Practice. To What End?

Xconomy

“Sure, we’d like to see more drugs available for patients,” said Scott Lippman, director of the Moores Cancer Center at the University of California, San Diego.