Xconomy

APRIL 17, 2019

Turning Point Therapeutics raised more than $166 million in its IPO, pricing at the top of its range and putting nearly 2 million more shares into the public markets than it had initially planned. million shares at $18 apiece, raising $166.5 million before discounts, commissions, and offering expenses.

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Xconomy

AUGUST 2, 2019

Investors, however, buoyed the company’s share price this week after Acadia (NASDAQ: ACAD ) announced it anticipated that sales of Nuplazid, its sole commercial drug, Read more » Reprints | Share: UNDERWRITERS AND PARTNERS.

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Xconomy

AUGUST 17, 2018

We also saw a new biotech emerge in the muggy New York heat, a couple deals for new flu vaccines, and interesting developments in the complicated world of drug pricing. Both were landmarks for the companies receiving the nod, Alnylam Pharmaceuticals and Amicus Therapeutics. It’s hot out there. Stay cool with the roundup.

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Xconomy

DECEMBER 4, 2017

9 announcement , the price of Dynavax shares slipped about 8 percent, from $20.05 To him, vaccines represent a paradigm in preventive health—even though vaccines take longer to develop and typically don’t bring. In the days following the company’s Nov. a share to $18.45

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Xconomy

JANUARY 5, 2018

Two other big questions we raised immediately became topics of conversation this week, thanks to Spark Therapeutics, which set the price for its gene therapy—the first ever approved in the U.S.—at We also covered gene therapy development news. —at $850,000. Read more » Reprints | Share:

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SoCal CTO

MARCH 22, 2007

skip to main | skip to sidebar SoCal CTO Thursday, March 22, 2007 Discussion Creation Among Bloggers - LinkedIn, Blogging and Discussion Groups Ive been participating in a Yahoo Group that are users of LinkedIn and who are Bloggers: [link] Its an interesting group of folks from diverse backgrounds. See Five Things Meme as an example.

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Xconomy

JULY 31, 2020

This week the neuroscience drug developer reached a deal to merge with publicly traded Arya Sciences Acquisition Corp II. The biotech IPO market is buzzing but Cerevel Therapeutics is showing that there’s more than one path to the public markets.

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Startup Professionals Musings

SEPTEMBER 16, 2022

Fixed price bidding is the only effective outsourcing model.” Getting a fixed price bid works for well-defined short-term projects, like blogging or programming. Fair compensation is the lowest price we can negotiate.” I’ll outsource software development, since I don’t understand it.” Be flexible.

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Outsource Development Outsource Summary Training 138

Xconomy

DECEMBER 10, 2018

The stock price of Mitek (NASDAQ:MITK) rose nearly 9 percent on the news, closing at $9.75. The company’s bread and butter has been licensing software for remote document capture, such as bank checks, but it is also developing a new business in digital identification verification. That’s according to a Nov.

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Xconomy

OCTOBER 26, 2018

Munich, Germany, hosted the annual conference of the European Society for Medical Oncology, where cancer drug developers unveiled the latest clinical data for experimental immunotherapies and drugs that treat the disease based on a tumor’s genetic signature. Read more » Reprints | Share:

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SoCal CTO

FEBRUARY 17, 2007

skip to main | skip to sidebar SoCal CTO Saturday, February 17, 2007 Finding Good Developers in Los Angeles? About 18 months ago, the entire group began to mention that they were having more difficulty finding good developers. Technology Advisor Technology Roles in Startups Pricing Customer Acquisition Sunk Costs and More -.

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Xconomy

JANUARY 31, 2020

million more shares than anticipated and pricing at the high end of its planned range. The stock price closed at $21.80, up 28 percent. The company joins the public markets with four product candidates in its pipeline, all topical non-steroidal treatments being developed for seven dermatological indications.

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Xconomy

AUGUST 25, 2017

But developments in health policy and life sciences march onward. This week saw some skirmishes in the drug price debate, new plans to expand the. Those of us who stepped outside with eclipse glasses, pin-hole projectors, or even colanders found a brief respite from the news.

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Startup Professionals Musings

MAY 1, 2021

Aspiring entrepreneurs ask me why their great idea hasn’t sold; they talk about it endlessly, and they expect others to do the development, finance, and marketing work for them. It can also be very inspiring, as you watch your dream morph into reality, or as you feel each little element of success: Watch your team develop new skills.

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TechCrunch LA

MARCH 19, 2021

Abodu began installing homes through a pre-approval process back in 2019, when the city of San Jose created a program that allowed developers of alternative dwelling units to submit plans for pre-approval to cut the time for homeowners. That approval process means that ADU developers like Abodu can be permitted in one hour.

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Xconomy

OCTOBER 27, 2016

Prices for agricultural commodities such as corn, soy, and wheat are at their lowest levels in years, but investment in agricultural technology has never been better. The increase in dollars flowing to agtech comes despite commodity prices that are down 65 percent from their 2013 peak, the report says. They also queried 15 VC firms.

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Xconomy

AUGUST 31, 2020

That price is a 60 percent premium to the Boston-based company’s closing stock price on Friday. Akcea develops drugs for rare diseases. The company currently has two commercialized products, along with others in its pipeline, some of which are in development with large. Read more » Reprints | Share:

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Both Sides of the Table

JULY 15, 2010

If you enjoy this blog I think you’ll enjoy watching the first 14 minutes of this video (just click on the image of me below). I give a sneak peek at a blog post I’m writing on the topic next week. . - No problem to have some developers in remote locations. If you watch the video I go into greater detail.

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Xconomy

MAY 16, 2018

A number of companies are developing drugs to block CGRP and stop migraine pain before it starts. But a common element is the abundance of a pain-inducing protein in the blood. During a migraine attack, nerves release this protein, called calcitonin gene-related peptide (CGRP).

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Xconomy

OCTOBER 28, 2016

. —Two Vertex rivals touted early-stage data at the NACFC conference: Belgium-based Galapagos , which is developing its own triple combination regimen, and Netherlands-based ProQr Therapeutics (NASDAQ: PRQR ), which is advancing an RNA-based CF drug sprayed into the lungs. THIS WEEK IN DRUG PRICING…. billion last year.

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Xconomy

SEPTEMBER 17, 2020

Dyne Therapeutics, a company developing genetic medicines for rare muscular disorders, has raised $233 million in an IPO that topped the preclinical-stage biotech’s projections. Late Wednesday, Dyne priced its offering of about 12.3 million shares at $19 each. The Waltham, MA-based biotech had previously planned to sell 10.3

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Xconomy

SEPTEMBER 9, 2016

The scientific goals, writ large, included nationwide data sharing among researchers and drug developers; better prevention through medicine (such as the HPV vaccine) and public education (anti-smoking campaigns); and a registry that could match cancer patients to trials based on genetics and other factors.

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Tech Zulu Event

SEPTEMBER 30, 2011

Lockboxer is a inventory and pricing service for your possessions. You can read my thoughts about their service on their blog. They can immediately price out anything they own and then use Lockboxer to sell directly to eBay, record any donations they need to make, or put together a home inventory. Absolutely.

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TechCrunch LA

OCTOBER 9, 2018

. “ Shipwell’s full-service, digitized brokerage platform can streamline the way many of our Anchor LPs and portfolio companies approach large-scale freight shipping,” the firm’s principal — and newest Shipwell board member — Vik Chawla wrote in a blog post announcing its most recent deal.

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Both Sides of the Table

MARCH 2, 2011

It’s apropos because there is so much noise these days with email, Twitter, Facebook, blogs, web shows, etc. I was thinking back to a few previous “insider baseball&# blog debates that raged for several weeks: AngelGate (aka Bin38 secret cabal), convertible debt vs. equity, bubble vs. not, and now the AngelList discussion.

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Startup Professionals Musings

DECEMBER 11, 2019

Fixed price bidding is the only effective outsourcing model.” Getting a fixed price bid works for well-defined short-term projects, like blogging or programming. Fair compensation is the lowest price we can negotiate.” I’ll outsource software development, since I don’t understand it.” Be flexible.

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Outsource Development Outsource Entrepreneur Summary 121

Xconomy

AUGUST 10, 2018

Two imminent FDA rulings on two separate drugs aren’t just noteworthy for the patients they’ll help, but the long and winding road their developers have taken to get to this point. First is Alnylam Pharmaceuticals, which has spent 16 years and over $2 billion to try to bring an unproven form of medicine, RNA interference (RNAi), to market.

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Xconomy

JANUARY 12, 2018

But the commercial challenge facing its developer, Spark Therapeutics, is daunting. After decades of research and scientific ups and downs, the first U.S. gene therapy, a single, long-lasting treatment called voretigene neparvovec (Luxturna) for rare, inherited blindness, is now on the market.

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Xconomy

FEBRUARY 21, 2020

The price of insulin, a life-saving treatment discovered a century ago, has been a flashpoint amid the broader drug pricing debate. The FDA is trying to tame high insulin prices by encouraging price competition. The FDA has historically regarded insulin as a drug.

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Startup Professionals Musings

SEPTEMBER 22, 2022

For example, many investors I know tell me they look for business plans that allocate the largest portion of a requested investment to marketing, but most often see the top “ use of funds ” to be further product or service development. Of course, you can’t possibly brand yourself if you don’t know who you really are.

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Xconomy

MAY 24, 2019

Patients, doctors, family members, and drug-price watchdogs continued to wait for the expected approval of Zolgensma , a Novartis (NYSE: NVS ) gene therapy for the rare inherited disease spinal muscular atrophy. Originally developed at a children’s hospital in Ohio , Zolgensma will be a litmus test for the nascent field.

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Xconomy

AUGUST 11, 2020

The larger company agreed to pay $12 per share for Pfenex (NYSE American: PFNX )—a 57 percent premium to its closing price Monday. San Diego-based Ligand (NASDAQ: LGND ) generates revenue from licensing deals and royalties paid by pharmaceutical companies that use technologies it develops or acquires for their own drug research.

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Xconomy

NOVEMBER 20, 2019

Drug pricing debates and uncertainty associated with Brexit are the issues most likely to keep biopharmaceutical executives awake at night. In turn, pricing pressure is also a concern as corporates and investors plan for the year ahead,”. Nevertheless, senior figures remain optimistic about the industry’s prospects in 2020.

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Xconomy

JUNE 3, 2019

Two weeks after raising $40 million to push ahead with its drug development programs, Inhibrx submitted paperwork to the SEC revealing that it aims to raise money in the public market, too. The La Jolla, CA-based company, which is developing protein drugs targeting cancer and other diseases, was founded in 2010.

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Both Sides of the Table

SEPTEMBER 25, 2010

When I first read Paul Graham’s blog post on “High Resolution&# Financing I read it as a treatise arguing that convertible notes are better than equity. As I’m generally a believer in ‘pricing rounds’ I initially didn’t agree with the premise of the post. Photo credit: D. rings true to me.

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Xconomy

JULY 24, 2020

EQRx launched in January during the JP Morgan Healthcare Conference with an audacious pledge to create 10 new drugs in as many years and then sell them at “dramatically” lower prices than existing medicines. Both drugs are anti-cancer molecules in mid-stage development that have been designed to hit known cancer targets. But not much.

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Both Sides of the Table

FEBRUARY 5, 2011

They like a solid product, well defined pricing, good references to sell against, a clear quota and well defined competitors. I’ve talked many times on my blog about how they’re the lifeblood of most businesses – even those that pretend like they’re above it all. Sales people will often blame your pricing.

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