On CAR-T’s Edge, Seattle Researchers Plot to Bypass Novartis Therapy
SEPTEMBER 19, 2017
It’s not a stretch to say that Greta Oberhofer is alive thanks to the genetically modified cell therapy called CAR-T. At three and a half months old, she was diagnosed with acute lymphoblastic leukemia, or ALL, an aggressive blood cancer. At 10 months old, she had a bone marrow transplant, which required chemotherapy. She had a bad reaction: Her kidney and liver shut down, and fluid built up in her heart and lungs. She was on a breathing machine.